| Author | Message | ||
     Juerg Moderator Username: Juerg Post Number: 3227 Registered: 04-2006 |
We welcome Martina Feldmann in our advisory board. She finished her Biochem . Lab degree at UVIC and now her immunology degree at UBC. She will over the next little while set together some ideas on point of care testing we try to integrate on Cortisol, testosterone ratio , as well as food intolerance assessment. This can than be combined with the nutritional step Mary Ann Kelly is working on to have a comprehensive tool for the " weak link " nutrition as a part of the ECGM model. In August Andri Feldmann will come to Canada from the University of Bern Switzerland to plan the longer term ideas and data collections for his Masters thesis and his Ph. D preparations on ECGM and how to integrate it into the common fitness market and personal training tools of every days person on teh street. We will keep you updated on all the upcoming steps and developpment in the next few month to come. | ||
| Juerg Moderator Username: Juerg Post Number: 3229 Registered: 04-2006 |
Well info goes fast. Martina has a full kit ready to go for cortisol and testosterone ration and daily profiling. This is heavily used in overweight people to see , whether there is a "fatigue" in the hormone balance existing so that catabolic reaction simply take over. Same could happened in people with a full time stressful job and a combined idea of training for events like a grand Fondo or others . The summation of a mental overload with wrong ratio of training/ recovery can unfortunately tip the scale into the more catabolic directions. We hope to have with Martina's help soon a system in place, where we can test fast and optimal hormonal profiles and reactions ,to find the best workout times as well as recovery times in combination with recovery of the ECGM systems. With the Cortisol profiling we hope to add with the help of Mary Ann as well the optimal nutritional intervention for recovery at the right time and with the proper food. This will move us back to an idea we discussed many many years back but we did not had the knowledge how to assess easy without big labs and institutions.  Hans Selye's idea of hormonal dys-balance may be now available for the person on the road ? | ||
| Juerg Moderator Username: Juerg Post Number: 3231 Registered: 04-2006 |
SHORT COMMUNICATION Diurnal cortisol profiles and evening cortisol in post-pubertal adolescents scoring high on the Children’s Depression Inventory B.R.H. Van den Bergh a,b,c,*, B. Van Calster d a Department of Psychology, Faculty of Social and Behavioural Sciences, Tilburg University, P.O. Box 90153, 5000 LE Tilburg, The Netherlands b Department of Psychology, Katholieke Universiteit Leuven, Tiensestraat 102, B-3000 Leuven, Belgium c Department of Welfare, Public Health and Family, Flemish Community, K. Albert II laan 35, B-1030 Brussel, Belgium d Department of Electrical Engineering (ESAT-SCD), Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, B-3001 Heverlee, Belgium Received 6 July 2008; received in revised form 9 December 2008; accepted 13 December 2008 Psychoneuroendocrinology (2009) xxx, xxx—xxx Summary Early-onset mood disorders have become a significant public health problem in recent years. The Children’s Depression Inventory (CDI) is a commonly used self-report measure. We studied the relation of CDI cut-offs to biological markers of depression such as the diurnal cortisol rhythm and evening cortisol. In 58 post-pubertal adolescents (29 boys and 29 girls, Mage = 15.1 years), the diurnal cortisol profile was derived from three saliva samples, collected at awakening, at noon and in the evening on a week-end day. Longitudinal repeated measurements regression revealed that the group with CDI > 18 (high depressive symptoms) clearly had a higher and flatter diurnal rhythm with elevated evening cortisol compared to either the group with CDI between 13 and 18 (moderate depressive symptoms) or CDI < 13 (low depressive symptoms). Multinomial logistic regression indicated that evening cortisol was useful in classifying the adolescents in the high depressive symptoms group, while awakening and noon cortisol were not. Our results indicate that the type of high flattened profiles sometimes seen in individuals who are clinically depressed according to diagnostic interviews can also be identified with a selfreport inventory, at high levels of symptom reporting. Given the complexity of conducting diagnostic interviews, this result bears clinical relevance. # 2008 Elsevier Ltd. All rights reserved. | ||
| Juerg Moderator Username: Juerg Post Number: 3232 Registered: 04-2006 |
Thanks , here for all interested groups the two options. http://www.stat.wvu.edu/~fdesta/auc.pdf | ||
| Juerg Moderator Username: Juerg Post Number: 3233 Registered: 04-2006 |
The effect of shift rotation on employee cortisol profile, sleep quality, fatigue, and attention level: a systematic review. Niu SF, Chung MH, Chen CH, Hegney D, O’Brien A, Chou KR. The effect of shift rotation on employee cortisol profile, sleep quality, fatigue, and attention level: a systematic review. J Nurs Res. 2011 Mar;19(1):68-81. Review. Abstract BACKGROUND: Disrupted circadian rhythm, especially working night duty together with irregular sleep patterns, sleep deprivation, and fatigue, creates an occupational health risk associated with diminished vigilance and work performance. PURPOSE: This study reviewed the effect of shift rotations on employee cortisol profile, sleep quality, fatigue, and attention level. METHODS: Researchers conducted a systematic review of relevant articles published between 1996 and 2008 that were listed on the following databases: SCOPUS, OVID, Blackwell Science, EBSCO Host, PsycINFO, Cochrane Controlled Trials Register, and CEPS. A total of 28 articles were included in the review. RESULTS: Previous research into the effects of shift work on cortisol profiles, sleep quality, fatigue, and attention used data assessed at evidence Levels II to IV. Our systematic review confirmed a conflict between sleep-wake cycle and light-dark cycle in night work. Consequences of circadian rhythm disturbance include disruption of sleep, decreased vigilance, general feeling of malaise, and decreased mental efficiency. Shift workers who sleep during the day (day sleepers) experience cortisol secretion increases, which diminish the healing power of sleep and enjoy 1 to 4 hours less sleep on average than night sleepers. Sleep debt accumulation results in chronic fatigue. Prolonged fatigue and inadequate recovery result in decreased work performance and more incidents. Rotation from day shift to night shift and its effect on shift workers was a special focus of the articles retained for review. CONCLUSIONS: Disturbed circadian rhythm in humans has been associated with a variety of mental and physical disorders and may negatively impact on work safety, performance, and productivity. | ||
| Juerg Moderator Username: Juerg Post Number: 3234 Registered: 04-2006 |
Here why we think it is a part of IP. This is an ever growing group of people we see, who are keen to get into a controlled health type of sport activities. An IP assessment will help to find limiter and compensator but a combination with a Cortisol profiling will help us to optimize rest and workout schedule to not overexert a sometimes already stressed out hormonal balance. : " CLINICAL STUDY Cortisol correlates with metabolic disturbances in a population study of type 2 diabetic patients Kerstin M Oltmanns2,4, Baerbel Dodt1, Bernd Schultes1, Hans H Raspe3, Ulrich Schweiger2, Jan Born4, Horst L Fehm1 and Achim Peters1 Departments of 1Internal Medicine I and 2Psychiatry and Psychotherapy, 3Institute for Public Health, and 4Department of Neuroendocrinology, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany (Correspondence should be addressed to K M Oltmanns, Department of Neuroendocrinology, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany; Email: Oltmanns@medinf.mu-luebeck.de) Abstract Objective: The prevalence of type 2 diabetes mellitus is increasing rapidly in industrialized countries, and adrenal glucocorticoids may intensify this disease. We sought to assess the relationship between diabetes-associated metabolic disturbances and cortisol concentrations in patients with type 2 diabetes. Design: We investigated 190 type 2 diabetic patients who volunteered from a population study of 12 430 people in Luebeck and its suburbs. The target population comprised men and women born between 1939 and 1958 who initially received a postal questionnaire about their health status. We identified 346 subjects with confirmed diabetes mellitus and 216 patients participated in the study. Patients with type 1 diabetes were excluded. Methods: Five salivary cortisol samples were collected before and after lunch, in the evening and then the next morning before and after standing. Clinical variables associated with diabetes were measured and correlated with cortisol concentrations. Results: None of the cohort had salivary cortisol concentrations that exceeded the normally accepted range. Based on cortisol samples collected just prior to a standard lunch, the cohort was divided into tertiles. Cortisol was positively related to: fasting blood, urinary and postprandial glucose; glycosylated hemoglobin; and systolic and diastolic blood pressures (all P , 0.05). Cortisol concentrations also correlated with the relative abdominal mass (P , 0.05) when patients with marked glucosuria were excluded. Conclusions: The degree of severity of several clinical measures of type 2 diabetes correlates with cortisol concentrations. Moreover, the results provide evidence for a positive relationship between metabolic disturbances and cortisol concentrations that are within the accepted normal range. European Journal of Endocrinology 154 325–331 | ||
| Juerg Moderator Username: Juerg Post Number: 3235 Registered: 04-2006 |
Thanks. I will move this discussion over to the Fact general discussion for further info. |